Searchable abstracts of presentations at key conferences in endocrinology

ea0035p339 | Developmental Endocrinology | ECE2014

Influence of growth hormone therapeutic supplementation on early hematopoietic stem/progenitor cells in patients with growth hormone deficiency (GHD).

Kawa Milosz , Stecewicz Iwona , Pius-Sadowska Ewa , Paczkowska Edyta , Piecyk Katarzyna , Gawrych Elzbieta , Petriczko Elzbieta , Walczak Mieczyslaw , Machalinski Boguslaw

Objectives: GH plays a crucial role in the regulation of metabolism of human cells. Nevertheless, a direct influence of this hormone on the proliferation, maturation and differentiation of human early hematopoietic stem/progenitor cells (HSPCs) has not been investigated thoroughly. Moreover, certain deviations of hematological parameters, such as anemia or leucopenia, are commonly observed in patients with growth hormone deficiency (GHD) syndrome, which might be substantially ...

ea0032p204 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

CNR1 polymorphisms and metabolic disorders in woman with PCOS-preliminary report

Milewicz Andrzej , Laczmanski Lukasz , Lenarcik Agnieszka , Kuliczkowska Justyna , Trzmiel-Bira Anna , Stachowska Barbara , Jedrzejuk Diana , Sadowska Ewa , Kolackov Katarzyna , Pawlak Maurycy , Arkowska Anna , Dorobisz Urszula , Hirmle Lidia , Lwow Felicja

The endocannabinoid system has been suspected to contribute to the association of visceral fat accumulation with metabolic diseases. Insulin resistance play important role in etiology in PCOS. The aim of our study was developed the role of CNR1 polymorphisms (rs806368, rs12720071, rs1049353, 806381, rs10485170, rs6454674, rs2023239) in metabolic disorders in woman with PCOS. 88 woman (20–35 years old) with PCOS (recognized using Rotterdam criteria) and 77 woman (20–3...